HEALING & RECOVERY
TB-500
Synthetic thymosin beta-4 fragment. Investigated in actin-binding and cytoskeletal repair literature.
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Certificate of Analysis
Third-party tested · ISO/IEC 17025 accredited
99.1%
purity
✓ Passed full QC panel
- Variant
- TB-500 · 10 mg
- Lot #
- AML-2026-0510
- Labeled
- 10 mg
- Tested
- 2026-04-18
Full QC panel
- Purity (HPLC)
- 99.1%
- Net Peptide Content
- Pass
- Identity (HPLC-MS)
- Confirmed
- Heavy Metals (ICP-MS)
- Not detected
- Sterility
- No growth
- Endotoxin (LAL)
- Within limits
Purity, lot and tested date are per-lot; remaining QC rows are representative — exact values on the CoA.
Compound Information
Chemical and structural properties
Chemical identity verified via NIH PubChem · biological targets characterized from the peer-reviewed literature.
Molecular profile
Structure
- CAS Number
- 77591-33-4
- Molecular Formula
- C212H350N56O78S
- Molecular Weight
- 4963 g/mol
- Sequence
- Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile (TB-4 active site)
- Type
- Research peptide
- PubChem
- CID 16132341 ↗
Biological targets
Interactions
- Primary target
- G-actin (actin-sequestering)
- Pathway
- Actin polymerization; cell migration; VEGF / angiogenesis
- Mechanism
- Thymosin β4 active-region peptide; binds G-actin and promotes cell migration
- Research area
- Tissue repair, cardiac and dermal wound research
Physical properties
Handling & Storage
- Appearance
- White to off-white lyophilized powder
- Solubility
- Soluble in sterile or bacteriostatic water; reconstitute prior to use
- Storage
- 2-8 deg C, protect from light
- Country of origin
- USA
Sources & References
Peer-reviewed research
Indexed in NIH PubMed. Provided for research context; not a claim of clinical outcome.
EXPERT OPINION ON BIOLOGICAL THERAPY
Thymosin β4: a multi-functional regenerative peptide. Basic properties and clinical applications
2012 · PMID 22074294
Goldstein AL et al.
View Source ↗ANNALS OF THE NEW YORK ACADEMY OF SCIENCES
beta-Thymosins
2007 · PMID 17468232
Hannappel E
View Source ↗INTERNATIONAL IMMUNOPHARMACOLOGY
Thymosin beta-4 denotes new directions towards developing prosperous anti-aging regenerative therapies
2023 · PMID 36709593
Bock-Marquette I et al.
View Source ↗EXPERT OPINION ON BIOLOGICAL THERAPY
Thymosin beta 4 and the eye: the journey from bench to bedside
2018 · PMID 30063853
Sosne G
View Source ↗CURRENT MEDICINAL CHEMISTRY
Thymosin β4: A Multi-Faceted Tissue Repair Stimulating Protein in Heart Injury
2020 · PMID 31333080
Bjørklund G et al.
View Source ↗
⚠ Important research notice
PRODUCTS ARE INTENDED AS A RESEARCH CHEMICAL ONLY. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only. Bodily introduction of any kind into humans or animals is strictly prohibited by law. Products should only be handled by licensed, qualified professionals. Products sold are not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug, food, or cosmetic.
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