AESTHETIC BLENDS
SNAP-8
Acetyl octapeptide-3. Investigated in topical cosmetic and SNARE-complex research.
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Certificate of Analysis
Third-party tested · ISO/IEC 17025 accredited
—
purity
✓ Passed full QC panel
- Variant
- SNAP-8 · 10 mg
- Lot #
- —
- Labeled
- 10 mg
- Tested
- —
Full QC panel
- Purity (HPLC)
- —
- Net Peptide Content
- Pass
- Identity (HPLC-MS)
- Confirmed
- Heavy Metals (ICP-MS)
- Not detected
- Sterility
- No growth
- Endotoxin (LAL)
- Within limits
Purity, lot and tested date are per-lot; remaining QC rows are representative — exact values on the CoA.
Compound Information
Chemical and structural properties
Chemical identity verified via NIH PubChem · biological targets characterized from the peer-reviewed literature.
Molecular profile
Structure
- CAS Number
- 868844-74-0
- Molecular Formula
- C41H70N16O16S
- Molecular Weight
- 1075.2 g/mol
- Sequence
- —
- Type
- Research peptide
- PubChem
- CID 76283482 ↗
Biological targets
Interactions
- Primary target
- SNAP-25 site within the SNARE complex (proposed)
- Pathway
- SNARE-complex assembly; vesicle docking and catecholamine exocytosis (proposed)
- Mechanism
- Acetylated, amidated octapeptide (acetyl octapeptide-3); extended SNAP-25 N-terminal mimetic
- Research area
- Topical cosmetic-peptide and neurosecretion research
Physical properties
Handling & Storage
- Appearance
- White to off-white lyophilized powder
- Solubility
- Soluble in water; reconstitute prior to use
- Storage
- 2-8 deg C, protect from light
- Country of origin
- USA
Sources & References
Peer-reviewed research
Indexed in NIH PubMed. Provided for research context; not a claim of clinical outcome.
JOURNAL OF CUTANEOUS AND AESTHETIC SURGERY
Polydioxanone Bioactive Sutures-Acetyl Hexapeptide-8 (Argireline): An Intelligent System for Controlled Release in Facial Harmonization
2023 · PMID 38314369
Velazco de Maldonado GJ et al.
View Source ↗JMIR DERMATOLOGY
Public Interest in Acetyl Hexapeptide-8: Longitudinal Analysis
2024 · PMID 38376906
Olsson SE et al.
View Source ↗AMERICAN JOURNAL OF CLINICAL DERMATOLOGY
The anti-wrinkle efficacy of argireline, a synthetic hexapeptide, in Chinese subjects: a randomized, placebo-controlled study
2013 · PMID 23417317
Wang Y et al.
View Source ↗JOURNAL OF COSMETIC AND LASER THERAPY : OFFICIAL PUBLICATION OF THE EUROPEAN SOCIETY FOR LASER DERMATOLOGY
The anti-wrinkle efficacy of Argireline
2013 · PMID 23464592
Wang Y et al.
View Source ↗EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES : OFFICIAL JOURNAL OF THE EUROPEAN FEDERATION FOR PHARMACEUTICAL SCIENCES
Topical delivery of acetyl hexapeptide-8 from different emulsions: influence of emulsion composition and internal structure
2015 · PMID 25497319
Hoppel M et al.
View Source ↗
⚠ Important research notice
PRODUCTS ARE INTENDED AS A RESEARCH CHEMICAL ONLY. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only. Bodily introduction of any kind into humans or animals is strictly prohibited by law. Products should only be handled by licensed, qualified professionals. Products sold are not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug, food, or cosmetic.
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