NEURO & NOOTROPIC
Semax Acetyl
Neuro and nootropic research peptide.
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Certificate of Analysis
Third-party tested · ISO/IEC 17025 accredited
99%
purity
✓ Passed full QC panel
- Variant
- Semax Acetyl · 30 mg
- Lot #
- TBD
- Labeled
- 30 mg
- Tested
- —
Full QC panel
- Purity (HPLC)
- 99%
- Net Peptide Content
- Pass
- Identity (HPLC-MS)
- Confirmed
- Heavy Metals (ICP-MS)
- Not detected
- Sterility
- No growth
- Endotoxin (LAL)
- Within limits
Purity, lot and tested date are per-lot; remaining QC rows are representative — exact values on the CoA.
Compound Information
Chemical and structural properties
Chemical identity verified via NIH PubChem · biological targets characterized from the peer-reviewed literature.
Molecular profile
Structure
- CAS Number
- —
- Molecular Formula
- —
- Molecular Weight
- 0 g/mol
- Sequence
- (see COA)
- Type
- Research peptide
Biological targets
Interactions
- Primary target
- BDNF / TrkB system; melanocortin pathway
- Pathway
- BDNF–TrkB; melanocortin; neurotrophin expression
- Mechanism
- N-acetylated, C-amidated Semax analog with enhanced metabolic stability
- Research area
- Cognition, neuroprotection research
Physical properties
Handling & Storage
- Appearance
- White lyophilized powder
- Solubility
- Soluble in water; reconstitute prior to use
- Storage
- 2-8 deg C, protect from light
- Country of origin
- USA
Sources & References
Peer-reviewed research
Indexed in NIH PubMed. Provided for research context; not a claim of clinical outcome.
BRITISH JOURNAL OF PHARMACOLOGY
Semax peptide targets the μ opioid receptor gene Oprm1 to promote deubiquitination and functional recovery after spinal cord injury in female mice
2025 · PMID 40692165
Liu R et al.
View Source ↗DOKLADY BIOLOGICAL SCIENCES : PROCEEDINGS OF THE ACADEMY OF SCIENCES OF THE USSR, BIOLOGICAL SCIENCES SECTIONS
Heptapeptide semax attenuates the effects of chronic unpredictable stress in rats
2013 · PMID 24385169
Yatsenko KA et al.
View Source ↗DOKLADY BIOLOGICAL SCIENCES : PROCEEDINGS OF THE ACADEMY OF SCIENCES OF THE USSR, BIOLOGICAL SCIENCES SECTIONS
The heptapeptide SEMAX stimulates BDNF expression in different areas of the rat brain in vivo
2003 · PMID 14556513
Dolotov OV et al.
View Source ↗JOURNAL OF NEUROCHEMISTRY
Semax, an analogue of adrenocorticotropin (4-10), binds specifically and increases levels of brain-derived neurotrophic factor protein in rat basal forebrain
2006 · PMID 16635254
Dolotov OV et al.
View Source ↗JOURNAL OF MOLECULAR RECOGNITION : JMR
Synacton and individual activity of synthetic and natural corticotropins
2017 · PMID 27921334
Vyunova TV et al.
View Source ↗
⚠ Important research notice
PRODUCTS ARE INTENDED AS A RESEARCH CHEMICAL ONLY. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only. Bodily introduction of any kind into humans or animals is strictly prohibited by law. Products should only be handled by licensed, qualified professionals. Products sold are not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug, food, or cosmetic.
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