NEURO & NOOTROPIC
P-21
Synthetic neurogenic peptide. Investigated in neurotrophic and hippocampal research literature.
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Certificate of Analysis
Third-party tested · ISO/IEC 17025 accredited
—
purity
✓ Passed full QC panel
- Variant
- P-21 · 5 mg
- Lot #
- —
- Labeled
- 5 mg
- Tested
- —
Full QC panel
- Purity (HPLC)
- —
- Net Peptide Content
- Pass
- Identity (HPLC-MS)
- Confirmed
- Heavy Metals (ICP-MS)
- Not detected
- Sterility
- No growth
- Endotoxin (LAL)
- Within limits
Purity, lot and tested date are per-lot; remaining QC rows are representative — exact values on the CoA.
Compound Information
Chemical and structural properties
Chemical identity verified via NIH PubChem · biological targets characterized from the peer-reviewed literature.
Molecular profile
Structure
- CAS Number
- 1246751-68-7
- Molecular Formula
- C27H42N6O8
- Molecular Weight
- 578.7 g/mol
- Sequence
- —
- Type
- Research peptide
- PubChem
- CID 56599151 ↗
Biological targets
Interactions
- Primary target
- No canonical receptor established; activity linked to leukemia-inhibitory-factor (LIF) signaling inhibition (proposed)
- Pathway
- LIF-signaling inhibition (proposed); BDNF expression; BDNF-linked GSK-3β modulation; hippocampal neurogenesis
- Mechanism
- Adamantylated tetrapeptide derived from the CNTF active-region peptide (P6)
- Research area
- Neurogenesis, synaptic plasticity, cognitive-aging research
Physical properties
Handling & Storage
- Appearance
- White to off-white lyophilized powder
- Solubility
- Soluble in sterile or bacteriostatic water; reconstitute prior to use
- Storage
- 2-8 deg C, protect from light
- Country of origin
- USA
Sources & References
Peer-reviewed research
Indexed in NIH PubMed. Provided for research context; not a claim of clinical outcome.
ALZHEIMER'S RESEARCH & THERAPY
Prevention of dendritic and synaptic deficits and cognitive impairment with a neurotrophic compound
2017 · PMID 28655344
Baazaoui N et al.
View Source ↗MOLECULAR NEURODEGENERATION
Neurotrophic factor small-molecule mimetics mediated neuroregeneration and synaptic repair: emerging therapeutic modality for Alzheimer's disease
2016 · PMID 27400746
Kazim SF et al.
View Source ↗NEUROBIOLOGY OF AGING
Rescue of cognitive-aging by administration of a neurogenic and/or neurotrophic compound
2014 · PMID 24702821
Bolognin S et al.
View Source ↗
⚠ Important research notice
PRODUCTS ARE INTENDED AS A RESEARCH CHEMICAL ONLY. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only. Bodily introduction of any kind into humans or animals is strictly prohibited by law. Products should only be handled by licensed, qualified professionals. Products sold are not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug, food, or cosmetic.
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