MITOCHONDRIAL & LONGEVITY
MOTS-c
Mitochondrial-derived 16-amino-acid peptide. Researched in metabolic-homeostasis literature.
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Certificate of Analysis
Third-party tested · ISO/IEC 17025 accredited
99%
purity
✓ Passed full QC panel
- Variant
- MOTS-c · 10 mg
- Lot #
- AML-2026-0524
- Labeled
- 10 mg
- Tested
- 2026-04-25
Full QC panel
- Purity (HPLC)
- 99%
- Net Peptide Content
- Pass
- Identity (HPLC-MS)
- Confirmed
- Heavy Metals (ICP-MS)
- Not detected
- Sterility
- No growth
- Endotoxin (LAL)
- Within limits
Purity, lot and tested date are per-lot; remaining QC rows are representative — exact values on the CoA.
Compound Information
Chemical and structural properties
Chemical identity verified via NIH PubChem · biological targets characterized from the peer-reviewed literature.
Molecular profile
Structure
- CAS Number
- 1627580-64-6
- Molecular Formula
- C101H152N28O22S2
- Molecular Weight
- 2174.6 g/mol
- Sequence
- Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg
- Type
- Research peptide
- PubChem
- CID 146675088 ↗
Biological targets
Interactions
- Primary target
- AMPK pathway; stress-dependent nuclear translocation
- Pathway
- AMPK; folate–methionine cycle; Nrf2 stress response
- Mechanism
- Mitochondrial-derived 16-amino-acid peptide; metabolic regulator
- Research area
- Metabolic homeostasis, exercise and aging research
Physical properties
Handling & Storage
- Appearance
- White lyophilized powder
- Solubility
- Soluble in water; reconstitute prior to use
- Storage
- 2-8 deg C, protect from light
- Country of origin
- USA
Sources & References
Peer-reviewed research
Indexed in NIH PubMed. Provided for research context; not a claim of clinical outcome.
FRONTIERS IN ENDOCRINOLOGY
MOTS-c: A promising mitochondrial-derived peptide for therapeutic exploitation
2023 · PMID 36761202
Zheng Y et al.
View Source ↗CELL METABOLISM
The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance
2015 · PMID 25738459
Lee C et al.
View Source ↗ADVANCED SCIENCE (WEINHEIM, BADEN-WURTTEMBERG, GERMANY)
Mitochondrial-Derived Peptide MOTS-c Suppresses Ovarian Cancer Progression by Attenuating USP7-Mediated LARS1 Deubiquitination
2024 · PMID 39321430
Yin Y et al.
View Source ↗PHARMACOLOGICAL RESEARCH
The mitochondrial-derived peptide MOTS-c relieves hyperglycemia and insulin resistance in gestational diabetes mellitus
2022 · PMID 34798268
Yin Y et al.
View Source ↗INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
MOTS-c, the Most Recent Mitochondrial Derived Peptide in Human Aging and Age-Related Diseases
2022 · PMID 36233287
Mohtashami Z et al.
View Source ↗
⚠ Important research notice
PRODUCTS ARE INTENDED AS A RESEARCH CHEMICAL ONLY. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only. Bodily introduction of any kind into humans or animals is strictly prohibited by law. Products should only be handled by licensed, qualified professionals. Products sold are not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug, food, or cosmetic.
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