Melanotan I

SEXUAL WELLNESS & PIGMENTATION

Melanotan I

Alpha-MSH analog (afamelanotide). Investigated in melanocortin-1 receptor and pigmentation research.

10 mgRUO · RESEARCH USE ONLY$39.00

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Certificate of Analysis

Third-party tested · ISO/IEC 17025 accredited

LATESTISO 170257+ TESTING

purity

✓ Passed full QC panel

Variant
Melanotan I · 10 mg
Lot #
Labeled
10 mg
Tested

Full QC panel

Purity (HPLC)
Net Peptide Content
Pass
Identity (HPLC-MS)
Confirmed
Heavy Metals (ICP-MS)
Not detected
Sterility
No growth
Endotoxin (LAL)
Within limits
VIEW COA →

Purity, lot and tested date are per-lot; remaining QC rows are representative — exact values on the CoA.

Compound Information

Chemical and structural properties

Chemical identity verified via NIH PubChem · biological targets characterized from the peer-reviewed literature.

Molecular profile

Structure

CAS Number
75921-69-6
Molecular Formula
C78H111N21O19
Molecular Weight
1646.8 g/mol
Sequence
Type
Research peptide

Biological targets

Interactions

Primary target
Melanocortin-1 receptor (MC1R); also MC3R, MC4R, MC5R
Pathway
MC1R–cAMP–PKA–MITF; tyrosinase-driven eumelanin synthesis
Mechanism
Linear [Nle4, D-Phe7]-α-MSH analog; non-selective melanocortin agonist
Research area
Pigmentation, photobiology and melanocortin-system research

Physical properties

Handling & Storage

Appearance
White to off-white lyophilized powder
Solubility
Soluble in water; reconstitute prior to use
Storage
2-8 deg C, protect from light
Country of origin
USA

Sources & References

Peer-reviewed research

Indexed in NIH PubMed. Provided for research context; not a claim of clinical outcome.

  • Afamelanotide

    2012 · PMID 38598652

    View Source ↗
  • BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

    Discovery of novel N-(1-benzyl-1H-imidazol-2-yl)amide derivatives as melanocortin 1 receptor agonists

    2022 · PMID 36367494

    Sato A et al.

    View Source ↗
  • POSTEPY DERMATOLOGII I ALERGOLOGII

    Afamelanotide in protoporphyria and other skin diseases: a review

    2024 · PMID 38784937

    Polańska A et al.

    View Source ↗
  • AMERICAN JOURNAL OF CLINICAL DERMATOLOGY

    Afamelanotide: A Review in Erythropoietic Protoporphyria

    2016 · PMID 26979527

    Kim ES et al.

    View Source ↗
  • JOURNAL OF MEDICINAL CHEMISTRY

    Discovery of MT-7117 (Dersimelagon Phosphoric Acid): A Novel, Potent, Selective, and Nonpeptidic Orally Available Melanocortin 1 Receptor Agonist

    2024 · PMID 39641249

    Sato A et al.

    View Source ↗

⚠ Important research notice

PRODUCTS ARE INTENDED AS A RESEARCH CHEMICAL ONLY. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only. Bodily introduction of any kind into humans or animals is strictly prohibited by law. Products should only be handled by licensed, qualified professionals. Products sold are not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug, food, or cosmetic.

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US Manufactured

Manufactured in our U.S. ISO Class 5 sterile facility under cGMP-aligned controls. Every step—from raw material qualification through final lot release—is completed domestically. Every production lot is batch-specific and fully traceable, ensuring consistent quality and manufacturing integrity.

Independent Testing

Every batch undergoes independent verification, including HPLC purity, mass spectrometry, endotoxin screening, sterility testing, heavy metals analysis, peptide identity confirmation, and quantitative peptide content. A complete Certificate of Analysis (COA) is published for every lot.

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Orders placed before 12:00 PM EST are typically shipped the same business day from our U.S. fulfillment facility, conveniently located near our manufacturing operations. Products are securely stored in a temperature-controlled environment and professionally managed to help preserve product quality, ensure rapid order fulfillment, and support time-sensitive research.

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