MITOCHONDRIAL & LONGEVITY
5-Amino-1MQ
Mitochondrial and longevity research compound.
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Certificate of Analysis
Third-party tested · ISO/IEC 17025 accredited
99%
purity
✓ Passed full QC panel
- Variant
- 5-Amino-1MQ · 50 mg
- Lot #
- TBD
- Labeled
- 50 mg
- Tested
- —
Full QC panel
- Purity (HPLC)
- 99%
- Net Peptide Content
- Pass
- Identity (HPLC-MS)
- Confirmed
- Heavy Metals (ICP-MS)
- Not detected
- Sterility
- No growth
- Endotoxin (LAL)
- Within limits
Purity, lot and tested date are per-lot; remaining QC rows are representative — exact values on the CoA.
Compound Information
Chemical and structural properties
Chemical identity verified via NIH PubChem · biological targets characterized from the peer-reviewed literature.
Molecular profile
Structure
- CAS Number
- 42464-96-0
- Molecular Formula
- C10H11IN2
- Molecular Weight
- 286.11 g/mol
- Sequence
- (see COA)
- Type
- Research peptide
- PubChem
- CID 66522933 ↗
Biological targets
Interactions
- Primary target
- Nicotinamide N-methyltransferase (NNMT)
- Pathway
- NNMT inhibition; NAD+ / SAM salvage; adipocyte metabolism
- Mechanism
- Small-molecule NNMT inhibitor
- Research area
- Metabolic, adipose and longevity research
Physical properties
Handling & Storage
- Appearance
- Yellow to off-white solid (small molecule)
- Solubility
- Soluble in DMSO or water
- Storage
- 2-8 deg C, protect from light
- Country of origin
- USA
Sources & References
Peer-reviewed research
Indexed in NIH PubMed. Provided for research context; not a claim of clinical outcome.
NATURE
NNMT inhibition in cancer-associated fibroblasts restores antitumour immunity
2025 · PMID 40702186
Heide J et al.
View Source ↗ARCHIVES OF PHARMACAL RESEARCH
Exploring NNMT: from metabolic pathways to therapeutic targets
2024 · PMID 39604638
Park J et al.
View Source ↗PHARMACOLOGICAL RESEARCH
Nicotinamide-N-methyltransferase inhibition improves cardiac function and structure in a heart failure with preserved ejection fraction mouse model
2025 · PMID 40484359
Li S et al.
View Source ↗MOLECULAR CANCER
NNMT promotes acquired EGFR-TKI resistance by forming EGR1 and lactate-mediated double positive feedback loops in non-small cell lung cancer
2025 · PMID 40089784
Dai J et al.
View Source ↗JOURNAL OF HEPATOLOGY
ER stress-induced upregulation of NNMT contributes to alcohol-related fatty liver development
2020 · PMID 32389809
Song Q et al.
View Source ↗
⚠ Important research notice
PRODUCTS ARE INTENDED AS A RESEARCH CHEMICAL ONLY. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only. Bodily introduction of any kind into humans or animals is strictly prohibited by law. Products should only be handled by licensed, qualified professionals. Products sold are not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug, food, or cosmetic.
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